Sex Differences in the External Urethral Sphincter Activity of Rats
نویسندگان
چکیده
Department of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan Department of Physical Medicine and Rehabilitation, Taipei Medical University Hospital, Taipei, Taiwan Department and Institute of Physiology, National Yang-Ming University, Taipei, Taiwan Neuroscience Research Center, Taipei Medical University Hospital, Taipei, Taiwan
منابع مشابه
Effects of two atypical neuroleptics, olanzapine and risperidone, on the function of the urinary bladder and the external urethral sphincter in anesthetized rats
BACKGROUND A previous report showed that the atypical neuroleptic clozapine resulted in marked changes in urodynamic parameters and greatly inhibited the activity of the external urethral sphincter in anesthetized rats. Such findings may help explain the high incidence of urinary disturbances reported during clozapine therapy. In an effort to extend our observations to other atypical neurolepti...
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In this study, we examined the possibility that 5-HT1A receptors may underlie sexually dimorphic mechanisms affecting the regulation of urethral functions in anesthetized rats. Simultaneous recordings of intravesical pressure under isovolumetric conditions, external urethral sphincter-electromyography, and urethral perfusion pressure were used to examine the effects of a 5-HT1A receptor agonist...
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In this work, we will study the Hurst parameter embedded in the discrete-time fraction Gaussian noise (DFGN) and derive the entropy with this parameter. It will be applied to the electromyogram (EMG) of external urethral sphincter (EUS). These signals come from intact rats and the injured ones from spinal cord injury (SCI). Analysis indicates that we can discriminate between intact and SCI rats...
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Coordination of the bladder detrusor and the external urethral sphincter is a supraspinally controlled reflex that is essential for efficient micturition. This coordination is permanently lost after spinal cord transection but can recover chronically after incomplete spinal cord injury (SCI). As glutamatergic transmission plays a key role in all levels of detrusor-external urethral sphincter co...
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BACKGROUND We previously showed that systemic administration of the atypical neuroleptic clozapine in the rat altered a number of urodynamic variables and inhibited the external urethral sphincter. Since clozapine acts at several receptor types both at the periphery and the central nervous system, the site of action remained uncertain. Therefore, the purpose of this study was to determine the e...
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